Doing clinical trials large enough to achieve adequate reductions in uncertainties about treatment effects.
نویسنده
چکیده
Some medical researchers and commentators on tests of medical treatments recognized more than two centuries ago that conclusions about the effects of treatments should be based on adequate numbers of people. From the middle of the 19th century onwards, the importance of the ‘law of large numbers’ became acknowledged increasingly within medical research. In 1840, for example, Jules Gavarret noted that:
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ورودعنوان ژورنال:
- Journal of the Royal Society of Medicine
دوره 106 2 شماره
صفحات -
تاریخ انتشار 2013